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Migration, diseases, and conflicts place undue pressure on health facilities in most border communities. These have implications for the health-seeking behaviour of border residents. Studies on border communities have focused largely on political and economic issues to the neglect of the health-seeking behaviour of dwellers. This study, therefore, examined the health-seeking behaviour of residents in selected border communities of south western Nigeria. The study adopted both quantitative (1,200 questionnaire) and qualitative (key informant interview and focus group discussion) in data collection techniques. Quantitative data were analysed using descriptive statistic and chi-square at p<0.05, while qualitative data were content analysed. Health-seeking behaviour of border residents was affected by cost and low access to modern Health care services resulting in increased patronage of alternative Health care services. Functional, adequate and affordable western Health care facilities should be provided and integrated with traditional Health care services.